What is Buprenorphine / Naloxone?
According to Wikipedia, Buprenorphine / naloxone (trade name Suboxone) is a combination drug formulation of buprenorphine, a μ-opioid receptor (MOR) weak partial agonist and κ-opioid receptor antagonist, and naloxone, a MOR silent antagonist, in a 4:1 ratio. It is used in the treatment of opioid dependence. The purpose of naloxone is to deter intravenous abuse; parenteral administration rapidly induces opioid withdrawal symptoms, while regular, intended use does not (as naloxone is minimally bioavailable with sublingual ingestion).
This combination is available as sublingual tablets or film. Suboxone sublingual strips and tablets are typically dissolved beneath the tongue. Other manufacturers (Bunavail) use varying buprenorphine/naloxone delivery methods, such as a buccal film that dissolves while attached to the cheek inside the mouth.
Most Common Medical Uses
Buprenorphine/naloxone is used for the treatment of opioid dependence in combination with psychosocial support and counseling for the patient. It has been found to be effective for treating opioid dependence, as is the first line medication according to U.S. National Institute on Drug Abuse. Due to the high binding affinity and low activation for the opioid receptor, cravings and withdrawal for opioids are decreased while preventing a patient from getting high and relapsing from using another opioid. Full article
Buprenorphine and Naloxone Used In Medication Assisted Treatment (MAT)
Suboxone was introduced to inpatient recovery many years ago, but came in vogue with outpatient treatment mostly in the last 10-12 years. Now, in conjunction with one-on-one therapy, Suboxone is used to stabilize the physical aspects of addiction, virtually eliminating withdrawals and cravings, allowing intensive therapy to resolve the psychological aspects of addiction. The result is a well-rounded combination that alleviates those addicted from the often painful physical side-effects associated with stopping of most any narcotic, while helping people resolve issues like trauma, abuse, anxiety, depression, and much more.
Nashville Suboxone Recovery utilizes MBA-level therapists that work one-n-one with patients, while a medical staff prescribes Suboxone, Bunavail, Zubsolv, generic buprenorphne & naloxone, as well as Subutex (buprenorphine without naloxone) which is used primarily with those who have highly-elevated liver enzymes and/or HEP-C.
If you’re tired of chasing pills, or heroin, and are ready to transform your life into something great, Nashville Suboxone Recovery can help you do it.
Call or text (615) 431-3701 today, or click the blue button lower right to schedule your Suboxone therapy online.
Appointments are typically available same day, but tend to fill-up quickly.
Make the call today. Change your life forever.
Leave a Comment